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การผลิต Med silk ครั้งที่ 1 (16-18 พย 63

Thai silk fibroin protein solution

laboratory and pharmaceutical grade

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MSDS

  • Supported by 10+ years of research with 50+ international publications

  • Sterile & Biocompatibility tested (ISO 10993)

  • Produced from a unique local Thai silk strain, maintained by Thailand’s national sericulture centres

  • Endless possibilities of usages in foods, cosmetics, pharmaceutics, and medicals.

Product details

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Standards

ISO 13485​

ISO 17025

ISO 14644-1:2015(E) Class5, Class 7 and Class 8 Cleanroom

ISO 9001

ISO 10993-5

Selected publications

  1. Okhawilai, M., et. al., Int.  J  Bio Macromol (2010)46: 544–550.

  2. Wongputtaraksa, T., et. al., J Biomed Mat  Res B (2012) 8:2307-2315.

  3. Kanokpanont, S., et. al., Int  J Pharm (2012)436: 141– 153.

  4. Vorrapakdee, R., et. al., J Mater Sci: Mater Med(2013) 24:735–744.

  5. Kaewprasit, K., et al., J Biomed Mater Res B, 2014. 102(8): p. 1639-47.

  6. Ratanavaraporn, J., et. al., J Mater Sci: Mater Med (2014) 25:401–410.

  7. Thitiwuthikiat, P., et. al., Tissue Eng. Part A. (2015)21:1309-1319.

  8. Lerdchai, K., et. al., J Pharm. Sci.(2016)105: 221-230

  9. Chancheewa, B., et.al., Mater. Today Commun. (2020)24:101044

  10. Laomeepol, C., et.al., Int.J. Pharm.(2020)589:11944

Form:                  Pale yellow solution (in sterilized water)

Mw:                    100-350 kDa (SDS PAGE)

Concentration:   20 mg/mL (1.96% by wt.)

Density:             0.965-1.086 g/ml

Zeta potential:   -3.81 to -3.95 (at pH7.4, 25 C, in deionized water)

pH:                     6.08-6.93 (at 25 °C, in deionized water)

Viscosity:           1.77-1.93 cP (at 25 °C, in deionized water)

Protein purity:     > 99.9% (Kieldahl)

Td:                      264.8 °C

Storage:              2-8 °C, no shaking

Storage time:     Up to 3 months at 4 °C

                           Up to 1 years at -20 C but some precipitations might occur upon                                     thawing

Sterility test:       Negative results for bacteria and fungus mycobacteria

Endotoxin:         <0.1 EU/ml

Source:              Silkworm cocoons; Thai domestic race, Bombyx mori CV. Nangnoi                                  Srisaket

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Manufactured by
Center of Excellence in Biomaterial Engineering for Medical and Health, Faculty of Engineering, Chulalongkorn University and Department of Medical Sciences, Ministry of Public Health, Thailand.

Tel: (+66) 02-218-6867 
Email: bemhru.chula@gmail.com
Website: http://www.bemhru.eng.chula.ac.th
 

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